I definately agree with everyones comments. If you follow Derek54's tips you should be fine. Once the snake gets use to your smell you can take her out of the cage and handle her a good bit. I handle mine everyday, except after feedings, then I wait 48 hours.The amount I handle her depends upon her activity. Some times she wants to just lay under my hands and chill out while looking out at me or watching tv every once and awhile, thats when I hold her for a good while because she is just calm and relaxed. Other times I can notice that she really doesn't want to be held because she is squirmy and so I don't hold her as much. Also, try not to have too much activity going on. Have few people in the room and turn the tv or radio down pretty low. Snakes are very sensitive to vibrations. Also don't try to restrain her too much. If she wants to go somewhere, I usually just let mine go. If you don't want her to go somewhere, just direct her with your hand to somewhere else instead of pulling her away. Odds are that she will just go back to that same spot until she finds out what is in that area. That is atleast how my snake is. If she wants to explore something, she will until I turn her in a different direction. Hope this helps.