Honestly, I'm not really the person to ask....seeing as I'm so new into this as well but I'll tell you what I think then hope I'm going in the right direction and that someone more advanced can answer it better for ya.
To my knowledge you should be able to pair them up continuously until she either sheds again or lays. But keep in mind you will want to keep them separate when they eat, and when they are in shed. The schedule I keep is, feed on monday or tuesday, then pair back up thursday-sunday. That way, they have time to digest their food in peace.
Also, if you male is being persistent, that could mean that she is ovulating. But not always, some males are just eager. The female gives off pheromones that tell the male its time to do the deed, so if he's going nuts around her, it could be she is ovulating, and your just not catching them hooking up.
So the short answer to your question is yes, I would continue to pair them up until she sheds. Then after she sheds, offer her food....if she refuses then that means she could likely be gravid....but put him in with her a few more days after she shed, just in case.
Hope that helps and it was the right advice!