I used to take Peaches out a LOT. I'm a sucker and feel bad for any creature that's stuck in a tank 24/7 (the reason I don't like fish lol) so when I first got her, I was handling her every second day except on feeding day and when she was digesting. I'd have her out for anywhere from 10 - 30 minutes and then I put her back, but I spot clean the cage in that time, change water, etc.
Now I don't take her out nearly as often or for as long, thanks to a much busier semester (2 weeks left, woo!). But occasionally now when I take her out, I set up a sort of playground on my coffee table out of cardboard boxes, extra tank decor I have laying around, etc. After I think she's had her fill of being handled by me, I put her on the coffee table while I do homework or something and let her slither around and explore. Once she curls up inside a box for more than 2 minutes, and starts to calm down, I put her back in her tank.
I'm blessed with the fact that she is terrific with being handled. I had never handled a snake before her (except for the tiny arse little garter I found outside and caught one time.. that was my first time discovering musk.. it was lovely..) and she was lovely with me, no aggression at all. I've had friends over who were wary of snakes and by the time they left they didn't wanna put her down and were taking selfies with her haha.